Dominique Blain lives and works in Montréal. Her work has been shown in several cities in North America, Europe and Australia (Biennale of Sydney in 1992). Three major retrospectives of her work were organized at the Musée d’art contemporain de Montréal in 2004 (travelling to the Mackenzie Art Gallery in Regina and to the Nickle Galleries in Calgary) and at the Musée national des beaux-arts du Québec in 1998 (travelling to the Ansel Adams Center in San Francisco and to the Sala 1 in Rome). Also, in 1997-1998, the Arnolfini Centre for Contemporary Arts in Bristol organized an exhibition at five U.K. institutions in Belfast, London, Edinburgh, Newcastle and Cambridge. Many museums have shown her work: Portland Museum of Art, Los Angeles County Museum of Art, Frankfurter Kunstverein; Stedelijk Museum in Amsterdam; Louisiana Museum in Copenhagen; European Museum in Brussels; and Museum of Science and Industry in Manchester. In Québec, she participated in three editions of Les Cent jours d’art contemporain and exhibited her work at Galerie de l’UQAM, University of Sherbrooke art gallery, Musée régional de Rimouski and Musée d’art de Joliette.

Dominique Blain has produced a series of public art installations in Québec, among them: Théâtre du Nouveau Monde, Montréal (2011); Montréal Museum of Fine Arts, Bourgie Pavilion (2011); Adresse symphonique, Montréal (2011); Théâtre d’Aujourd’hui, Montréal (2010); Hôpital du Sacré-Coeur, Montréal (2009); Jewish General Hospital, Montréal (2008); Reford Gardens, Grand-Métis (2007); Quartier International, Montréal (2006); Bibliothèque et Archives nationales du Québec, Montréal (2005); Sinclair Laird School, Montréal (2000); Maison des écrivains, Montréal (1991); and at the headquarters of the Canadian Broadcasting Corporation, Toronto (1994).