After a year studying graphic design at the Catholic University of Chile, in Santiago, Rafael Sottolichio undertook a diploma in visual arts at the CÉGEP de Saint-Laurent in Montreal in 1991. He earned a BFA in 1996 and an MFA in 2009 at the Université du Québec à Montréal. Sottolichio has had work in numerous solo and group exhibitions. He has produced a number of murals, including including La maison que nous avons bâtie (The House That We Have Built) in 2007 for the Integration of a Public Work of Art Competition and the Pere-Marquette Centre in the borough of Rosemont-La-Petite-Patrie, and the one for the Patro Le Prévost community and recreation centre, Ensemble, in 2009.
He is represented by the Lacerte Contemporary Art Gallery.